Rex, an AI-native service deploying specialized agents to manage enterprise order-to-cash operations, launched in 2026 with backing from Y Combinator and Vercel. Founded by Merlin Kafka and Lewis Blac…
Infera, an AI-native laboratory operating system startup founded in 2026 and backed by Y Combinator, converts natural language experiment descriptions into validated protocols, material orders, instru…
Instinct, a Y Combinator Winter 2026 company, launched a mobile trading app that uses AI and quantitative tools to help retail traders act on their instincts in global and crypto markets. Founded by f…
RealPact, a Y Combinator Summer 2026 company founded by Dartmouth students, has launched voice-powered AI agents that automate real estate transactions by retrieving property records, filling contract…
Zenbu, a Y Combinator Spring 2026 company founded by former Next.js core team member Rob Pruzan, launched an extensible IDE purpose-built for managing AI coding agents. The tool addresses operational …
Care GP, a Y Combinator Summer 2026 company, has deployed AI agents to automate administrative tasks in over 400 Australian GP clinics, reducing burnout and wait times. The platform integrates with cl…
Cerenovus, a Y Combinator Summer 2026 company founded by Harvard students, is building an AI-powered 'company brain' that aggregates and reasons over fragmented enterprise data from emails, Slack, doc…
Linzumi, a Y Combinator Spring 2026 company, launched a chat interface that lets engineering teams coordinate AI coding agents running locally on their own machines, addressing security concerns of cl…
Touchmark, a Y Combinator Summer 2026 startup, is building infrastructure to price AI outputs based on quality and delivered value instead of token count. The company offers a TypeScript SDK that reco…
Mireye, a Y Combinator Summer 2026 startup, is building a geospatial data infrastructure layer that provides AI agents with accurate, cited ground truth about physical locations. The company, founded …
Tolmo, an AI security startup, emerged from stealth in June 2026 with a $22M seed round led by Accel and Y Combinator. The company builds autonomous AI security agents that operate on a live knowledge…
Pango, a Y Combinator S26 startup, launched an agentic operating system that automates post-purchase operations for e-commerce brands, including returns, exchanges, and delivery tracking. Founded in 2…
Six major infrastructure companies—Cloudflare, Shopify, Stripe, Supabase, Netlify, and Google—independently invested in making their platforms agent-ready over the past six months, signaling a new dis…
Vanta, an agentic trust platform, crossed $300M in ARR by integrating AI into its security and compliance product, a domain where trust is traditionally hard to earn. The company learned to trust AI b…
Osmaura, a Y Combinator Summer 2026 company founded by MIT alumni Kali Abeje and Jity Woldemichael, launched an AI engine that provides law firm partners with rainmaker-level business development supp…
Exa launched Exa Agent on June 16, transforming its AI-native search API into a research agent endpoint for developers. The product automates structured web research tasks like deep research and entit…
Y Combinator's Spring 2026 Demo Day saw investors gravitating toward startups that turn AI into durable control systems for defense, agent infrastructure, and healthcare, with some companies commandin…
Posting Machine, a content agency using AI, enables two people to manage 20 LinkedIn accounts for B2B SaaS founders by turning customer calls, meeting notes, Slack threads, and product updates into fo…
Conduit, an AI-powered hospitality technology company, launched a platform to automate daily operations for hotels, serviced apartments, and short-term rentals. The platform includes pre-built AI agen…
Baran Ozkan spent 15 months searching for compliance software that didn't exist, so he built Flagright, an AI operating system for financial-crime compliance. The startup has raised $12.5 million in S…