Cas9

Researchers at Peking University and East China Normal University used AlphaFold3 to redesign CRISPR base editors, reducing off-target activity from 28% to 5% in one comparison while preserving on-tar…

Researchers used AlphaFold AI to redesign gene-editing proteins, reducing off-target effects that cause safety concerns in therapies. The team modified key areas of Cas proteins identified by the AI t…