Researchers at Peking University and East China Normal University used AlphaFold3 to redesign CRISPR base editors, reducing off-target activity from 28% to 5% in one comparison while preserving on-tar…
A new AI framework called ContactSeek uses Google DeepMind's AlphaFold3 to redesign gene-editing proteins, achieving dramatically higher accuracy than existing high-fidelity alternatives. Published in…
Evo Design released proto-tools, an open-source Python package that provides a unified interface for computational biology and biological AI tools, eliminating dependency conflicts by running each too…
Isomorphic Labs, a Google DeepMind spinoff, has developed a new AI system called the Isomorphic Drug Design Engine (IsoDDE) to identify hidden binding sites on proteins that standard models like Alpha…
Deep neural networks have enabled generative modeling of biomolecules, with models like AlphaFold3 and Chai-2 now capable of predicting and designing drug-like molecules and antibodies. However, resea…