It depends on what you want to do with the phone.
I got a Pixel 10 last week, my previous phone was a Pixel 6 that has been running Graphene OS. On the old phone all my apps were installed before Google Integrity API became a requirement, and on the new phone a lot of the apps I need stopped working in Graphene OS.
I had Claude write a runbook for removing the Google apps and AI features from the phone, and then I gave the runbook to Hermes and hooked it up to the phone with adb.
It did a pretty good job at removing all the Google apps, and replaced needed apps with fossify and FUTU, etc.
source & further reading
forum.level1techs.com — original article
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