ProteinMPNN

A new benchmark called ABLE, introduced in arXiv paper 2609.05818v1, evaluates how well LLM agents use biological AI models such as ProteinMPNN and AlphaFold3 in dual-use protein design workflows. Tes…

Anthropic reported that its Claude AI system autonomously designed de novo protein binders with a 27% experimental hit rate across most targets tested, using the new Claude Science platform launched o…

A Nature study published July 22 combined ProteinMPNN redesign with laboratory evolution to produce botulinum neurotoxin proteases that were more stable and better able to acquire new functions than n…