PLOS Computational Biology published a research article on July 30, 2026, describing a spiking neural-network model that combines sampling-based probabilistic inference with attractor dynamics in the …
PLOS Computational Biology published SynAPSeg on July 29, an open-source dataset and Python framework for detecting and measuring synaptic puncta in fluorescence microscopy images. The authors report …
PLOS Computational Biology published ALFAssay on July 27, a feed-forward neural-network pipeline that estimates circulating tumor DNA fractions from cell-free DNA fragmentation profiles in breast canc…
PLOS Computational Biology published a study on July 9, 2026, deriving a closed-form rule for spiking neurons to control linear dynamical systems by emitting spikes only when they move the system clos…
PLOS Computational Biology published a study on July 9, 2026, presenting an embedding-guided method that uses protein-language-model embeddings with Monte Carlo sampling to navigate enzyme sequence sp…
Researchers applied machine learning to whole-genome sequences of 299 Borrelia burgdorferi clinical isolates, identifying protein variants in five adhesins (BBK32, DbpA, OspC, P66, RevA) strongly asso…
A new collection in PLOS Computational Biology, introduced by Alber, Smith, Laubenbacher, and Merks on June 4, 2026, surveys the use of digital twins and multi-scale modeling in predictive biology and…