The Zen of mGPU A user reports achieving 407 FPS in Batman: Arkham Knight at 4K with max visuals and PhysX by using a dual-GPU setup with two RTX 5090s, running DLSS 5 on the second GPU via a Neural CoProcessor, and using Lossless Scaling, along with a PowerShell script to automate launching and cleanup. so some real examples using Batman Arkham Knight. Older, yet elegant and refined game with lore and graphics that stand the test of time. . So the base line for the game includes DLSS5, dual 5090 RTX, the associated rig, and the Neural CoProcessor to run DLSS 5 on the 2nd GPU , also specifically running PhysX on 2nd GPU , and Lossless Scaling on 2nd GPU . 407 FPS max visuals, Physx, 4K I don’t like things running in the background when not needed, so I make shortcuts to launch and close the Lossless Scaling with the game start/and end. An example script to render the game itself on GPU1, but do Lossless Scaling on GPU2, Physx on inspector setup GPU2, and DLSS5 on GPU2 neural coprocessor Shortcut modification to launch Arkham Knight: Explicit File Execution Paths $LSPath = “C:\Program Files\LS\LosslessScaling.exe” $GamePath = “D:\Batman\Binaries\Win64\BatmanAK.exe” 1. Spawn Lossless Scaling hidden into the background tray space Start-Process -FilePath $LSPath -WindowStyle Hidden 2. Safety pause to guarantee LS hook engine is listening in the tray Start-Sleep -Seconds 5 3. Launch the game engine binary targeting your primary discrete hardware $GameObject = Start-Process -FilePath $GamePath -ArgumentList “-graphicsadapter=1” -PassThru 4. Wait for the black screen to stabilize and the audio engine to spin up Start-Sleep -Seconds 6 5. THE BLACK SCREEN FIX : Inject a Windows Key tap to flush the graphics pipeline This automates your manual fix and forces DWM to draw the frame layers instantly. $WshShell = New-Object -ComObject WScript.Shell $WshShell.SendKeys “^{ESC}” Sends Ctrl + Esc The native Windows global equivalent to the Win Key 6. Wait a split second for the Start Menu overlay to trigger the desktop refresh, then clear it Start-Sleep -Milliseconds 400 $WshShell.SendKeys “^{ESC}” Tap it again to instantly dismiss the menu layout 7. Script thread blocks execution here until the game process exits $GameObject.WaitForExit 8. Cleanup Trigger: Force kill Lossless Scaling to flush system RAM pools Stop-Process -Name “LosslessScaling” -Force Also, I have expanded HD textures and effects and other components for better visuals such as prerequisites: Arkham Knight community patch / fix Arkham Knight HD Texture Pack Arkham Knight 8K Ultra HD assorted individual mods / textures Combined result is these settings, using 2nd GPU, 4K, is 407 FPS on the built in benchmark So use three utilities if you want it easy, play with sliders as you see fit: Lossless Scaling Neural Coprocessor, to run DLSS 5 on 2nd GPU One Click DLSS 5 injection OS MS Windows Server 2022 Data Center as workstation Hardware: 2x 5090 RTX Gigabyte OC Edition 2x AMD 9684X Epyc 192/384 cores 2.2GB of L3 cache , Gigabyte MZ73-LM2 Dual socket motherboard, PCIE 5.0 1.5 TB RAM DDR5 ECC LRDIMMs , 2800W psu 4x Micron 9300 Max RAID / 64TB volume Samsung 9100 Pro 8TB 8TB . 2x Back up drives Micron 5300 16TB Asus PA32UCG-K monitor, MS Data Center 2022 & 2025 & Ubuntu, Air cooled, cool temps, small case, ultra quiet operation