{"slug": "the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete", "title": "The world’s largest ‘biological datacenter’ could help make animal testing obsolete", "summary": "Vivodyne, a startup based south of San Francisco, operates the world's largest 'biological datacenter' with a dozen robotic labs called 'hives' that can run controlled trials on more than 3 million human tissues per year, twice the capacity of all U.S. clinical trials combined. The system uses AI-designed experiments on human tissue grown on biological chips to better predict drug safety and efficacy, potentially making animal testing obsolete. CEO Andrei Georgescu says the technology has already stopped development of some unsafe drugs and is working with many of the largest pharmaceutical companies.", "body_md": "There’s a big flaw in the way that drug companies develop and test medicines today: What works in a mouse often doesn’t work in a human.\n\nFor decades, the industry has relied on animal testing. But in a laboratory south of San Francisco, a startup called [Vivodyne](https://www.vivodyne.com/) is scaling up a different approach. Inside wardrobe-size mini labs, robots grow human tissue and run thousands of [AI](https://www.fastcompany.com/section/artificial-intelligence)-designed experiments that could better predict how well a new drug will work—and whether it will be safe.\n\nRight now, around 90% of [clinical trials](https://www.fastcompany.com/91553327/curing-10000-diseases-in-our-lifetime) fail despite the fact that a drug has already successfully gone through animal testing. “You have these clinical trials where there’s hundreds of millions of dollars at stake, and decades of people’s careers just spent hoping this thing works,” says Andrei Georgescu, Vivodyne’s CEO. “And then it fails because of some ambiguity that you could not have checked.”\n\nThe company’s system, which now includes a dozen robotic labs called “hives,” can run controlled trials on more than 3 million human tissues each year. That’s twice the capacity of all the clinical trials in the U.S. combined.\n\nThe process starts with cells from humans, often taken from a blood draw. In its labs, the cells grow on “[biological chips](https://www.fastcompany.com/90775704/how-human-organs-on-a-chip-can-help-replace-animal-testing)” and self-assemble into living structures with blood vessels and immune cells that reproduce some of the functions of the original organ, whether that’s a liver or a kidney. (The tissues don’t look like full-size organs, but like large biopsies, with hundreds of thousands of cells.)\n\nThe automated system can deliver drugs to the tissues, dose with cell therapies, knock out genes, and run complex tests and analysis. AI can design experiments and then use the results to continually design new experiments and improve.\n\n“We can dose with tens and tens of thousands of therapeutic compounds to understand what they would do in that particular tissue type within a person, and we can repeat this across many types of tissue,” Georgescu says. “We can look at diseased tissue and see if it becomes healthy. We can look at healthy tissue and see if there are side effects from these drugs.” At a more fundamental level, it’s possible to begin to understand the human body in a way that wasn’t possible before, because experiments in humans have inherently been limited.\n\nOther startups also use human tissues for testing, but Vivodyne’s platform can be up to 1,000 times larger, making it possible to capture more of the complexity of human biology. In addition, the company can run a massive number of experiments in parallel and feed the data back into AI to repeatedly design new experiments.\n\nAlready, the company is working with many of the largest drug companies. Though Georgescu couldn’t share specific details, he says that the technology has already stopped the development of some drugs that would have been unsafe. Vivodyne has also helped pharmaceutical companies select targets for new drugs and optimize delivery vehicles.\n\nA clinical trial might test one drug in thousands of people. Vivodyne can test thousands of different drugs across human tissues at once. And while people in a drug trial only have occasional visits to a clinic to track results, the system can continually test how human tissue responds.\n\nThe process is also faster than running animal tests. If a drug company is trying to discover a new target for a disease, for example, it might use genetically modified mice. But just waiting to get the modified mice can take a year and a half, and then there’s the actual testing. “By that time, we’ve done 25 cycles of our own tests,” Georgescu says.\n\nFor nearly a century, U.S. law required animal testing before human clinical trials in drug development; that changed in 2022 with the [FDA Modernization Act](https://www.scienceadvancement.org/reflections/what-does-the-passing-of-the-fda-modernization-act-2-0-mean-for-animals-in-basic-research/). In the short term, Georgescu says, animal testing will continue in parallel. But it likely won’t be long before it’s a thing of the past. “The failure rate is so high from animals, I think any alternative is going to very quickly dominate,” he says.", "url": "https://wpnews.pro/news/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete", "canonical_source": "https://www.fastcompany.com/91589344/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete", "published_at": "2026-08-13 09:11:00+00:00", "updated_at": "2026-08-13 09:36:10.346302+00:00", "lang": "en", "topics": ["artificial-intelligence", "ai-products", "ai-infrastructure"], "entities": ["Vivodyne", "Andrei Georgescu"], "alternates": {"html": "https://wpnews.pro/news/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete", "markdown": "https://wpnews.pro/news/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete.md", "text": "https://wpnews.pro/news/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete.txt", "jsonld": "https://wpnews.pro/news/the-worlds-largest-biological-datacenter-could-help-make-animal-testing-obsolete.jsonld"}}