arXiv:2610.32151v1 Announce Type: new Abstract: Large language model agents that use tools could take on part of the electronic health record and desk work that occupies physicians' time, but in many hospitals the medical information systems run inside closed networks, so the model and the agent harness must also sit inside. We designed, implemented, and deployed LLENS, a clinical support AI agent platform that runs inside the closed network of Hokkaido University Hospital on one host with 8 NVIDIA H200 GPUs, the open-weight model Kimi K2.6 (~1 trillion parameters), and a web application rebuilt from Open WebUI. The harness has 10 components, including page image reading, full-text attachment input, a path-addressed document tree without a vector index, a network-isolated sandbox, artifact return, self-checking of generated output, subagents, and saved procedures. Kimi K2.6 was chosen from 3 open-weight candidates and scored 480/500 on the 2026 Japanese Medical Licensing Examination; it generated 119 tokens/s for one user and served 16 concurrent requests at 908 tokens/s in total. On 180 questions over hospital documents (3 seeds each), mean accuracy was 10.7% with no documents, 81.3% with fixed retrieval (top 10 chunks of one lexical search), and 97.2% with interactive access, in which the model reads with document tools and the sandbox (15.9 percentage points above fixed retrieval, 95% CI 10.9-21.3); the difference lay in filtering/counting questions (16.7% vs 87.8%). Five scenarios with synthetic data ran on combinations of the components: needlestick injury response, batch adverse event grading, scanned referral letter transcription, falls data aggregation and plotting, and investigation of 3 topics by subagents. The platform has run on the hospital network since September 14, 2026.
The LLENS Platform for On-Premises Large Language Model Agents in a Japanese University Hospital: Development and Evaluation Study
Hokkaido University Hospital researchers designed, implemented and deployed LLENS, a clinical support AI agent platform running entirely inside the hospital's closed network on a single host with 8 NVIDIA H200 GPUs and the open-weight Kimi K2.6 model (~1 trillion parameters), the platform running on the hospital network since September 14, 2026. On 180 questions over hospital documents (3 seeds each), the agent scored 97.2% mean accuracy with interactive document-tool access versus 81.3% with fixed retrieval and 10.7% with no documents, a 15.9 percentage-point gain (95% CI 10.9-21.3) concentrated in filtering and counting questions (87.8% vs 16.7%). Kimi K2.6, chosen from 3 open-weight candidates, scored 480/500 on the 2026 Japanese Medical Licensing Examination and generated 119 tokens/s for one user, serving 16 concurrent requests at 908 tokens/s in total.
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