Show HN: Enzyme – a programming language that compiles wikis for agents A developer released Enzyme, an open-source programming language that compiles a Markdown notes folder into a local search index for coding agents such as Claude Code and Codex, letting them retrieve and cite related notes written over months. Enzyme installs via a curl script from its GitHub repository (byenzyme/enzyme) and an agent-specific command (`enzyme install claude`, or codex, hermes, openclaw), then reads an editable `.enzyme` settings file specifying which folders, tags and links to index. The tool generates "catalysts" — questions sampled from excerpts across time — via `enzyme petri` and ranks notes by wording and meaning together via `enzyme catalyze`, with search running entirely on the user's machine. Enzyme helps your coding agent work from your notes. It reads how your Markdown notes are already organized folders, tags, links, and dates and builds a local index, so Claude Code or Codex can pull up related notes from months of writing and cite them. Open your Markdown notes folder in Claude Code, Codex, or another agent that can run terminal commands, and paste this prompt. If your agent is open elsewhere, give it the path to your notes. Set up Enzyme for the Markdown notes folder I have open. If you cannot identify it, ask me for its path. Install Enzyme if needed using https://raw.githubusercontent.com/byenzyme/enzyme/main/install.sh, and install the instructions for this agent. Read and follow the installed enzyme-workspace-setup skill. You may use Enzyme's online service to suggest settings from my notes and prepare search. Show me what you propose to include or exclude, and let me correct it before building the local search index. Then answer one useful question using my notes, with links to the sources, and suggest a question I can ask next. Keep my existing notes in place and unchanged. Ask separately before any cleanup, model download, or recurring task. Your agent installs Enzyme and follows its setup skill. It proposes which folders, tags, and links to read, shows you the settings so you can correct them, builds the index, and answers one real question with links to the notes behind it. Your notes stay where they are, and you don't need to clean them up first. After setup, keep working with your agent as usual. The installed skill tells it when to search with Enzyme, when plain search is better, and when to run enzyme refresh so new notes are included. Prefer to install it yourself first? Run this, then paste the same prompt: curl -fsSL https://raw.githubusercontent.com/byenzyme/enzyme/main/install.sh | bash cd /path/to/your/notes enzyme install claude or: codex, hermes, openclaw Enzyme was built for knowledge bases that grow quickly: - Obsidian vaults that accumulate dated notes in a few folders - Meeting notes and AI-native, Markdown CRM setups - Agent memory written as Markdown It helps most when a question spans many notes written over time: what changed in a project, what keeps coming up with a person, why a decision went the way it did. For a name, title, or exact phrase, plain search is faster, and the installed skill tells your agent to use it. Setup saves a short, editable settings file an .enzyme program that says what to read. When the index is built, Enzyme does two things: 1. Maps what matters. It samples excerpts across time from each folder, tag, or link you chose and writes questions from them, called catalysts , about what you decided, changed, or left open there. enzyme petri shows this map. 2. Indexes every note for search. enzyme catalyze ranks notes by wording and meaning together, so a search finds the passage whether your agent names something exactly or only describes it. Each result carries the catalyst that best connects it to the query. Search runs entirely on your machine. Your agent orients on the map, searches from several angles, and answers from your own passages, so it can tell you how your thinking moved, not just what one note says. Catalysts are generated, so they're hints, never evidence: judge setup by the notes your agent brings back. A small settings file looks like this. Your agent writes and edits it with you during setup: workspace "notes" { source markdown "notes" { path "~/notes" } learn questions from folder "people" including linked pages about relational learn questions from folder "meetings" about operational learn questions from tags "startup", "design" about decision trace } Each reading uses a profile that sets what to look for. The built-in profiles were refined over 2 years of personal use https://joshpham.com/kit/how-i-use-enzyme : | Read... | For... | Profile | |---|---|---| | Project notes | what's stuck and what keeps blocking | operational | | Decision records | why a choice won, what would change it | decision trace | | Saved articles | connections to what you're already working on | resonance trace | | Journals | what keeps returning across entries | reflective | | People notes | what matters in these relationships | relational | | Feedback / activity logs | what works for you, under what constraints | preference evidence | | default | costs, assumptions, live tensions | tension trace | enzyme compile -v Review the .enzyme settings file at the path printed by compile. enzyme init --quiet enzyme doctor enzyme catalyze "a question about your notes" compile proposes settings and saves them; init builds the local index from them; doctor reports what was indexed and any problems. For Apple Notes, a preset builds a named workspace program from your Notes database. Review the saved .enzyme program before running init : enzyme --workspace apple-notes compile --preset apple-notes \ "$HOME/Library/Group Containers/group.com.apple.notes/NoteStore.sqlite" enzyme --workspace apple-notes init For Are.na, use enzyme --workspace