Scaling Qualitative Analysis with Large Language Models: Development and Validation of the Smart Coder Framework for Human-LLM Collaborative Coding Researchers proposed the Smart Coder Framework, a three-phase approach to human-LLM collaborative qualitative coding structured around Instruction, Prompt Strategy, and Reliability Check, and validated it on 72 middle-school mathematics teacher interview transcripts against a human-consensus benchmark. In a factorial design, 12 transcripts were used for prompt development and calibration and 60 for formal evaluation, comparing instructed versus uninstructed prompts, few-shot versus few-shot plus chain-of-thought prompting, and single-pass versus self-consistency coding. Instruction consistently improved agreement, chain-of-thought further improved agreement under adequate instruction, and self-consistency produced smaller, theme-dependent gains while helping flag unstable decisions for human review, with performance also varying by transcript characteristics. arXiv:2610.33205v1 Announce Type: new Abstract: Current uses of large language models LLMs for qualitative coding often rely on ad hoc prompting with limited guidance for reliability and human oversight. To address these limitations, we propose the Smart Coder Framework, a three-phase approach structuring human-LLM collaborative coding through Instruction, Prompt Strategy, and Reliability Check. We evaluated the framework using 72 middle-school mathematics teacher interview transcripts and a human-consensus benchmark. A factorial design compared instructed versus uninstructed prompts, few-shot versus few-shot plus chain-of-thought prompting, and single-pass versus self-consistency coding. Twelve transcripts were used for prompt development and calibration, and 60 for the formal evaluation. In the results, instruction consistently improved agreement. Chain-of-thought further improved agreement under adequate instruction, and self-consistency produced smaller, theme-dependent gains but helped identify unstable decisions for human review. Performance also varied by transcript characteristics. Overall, the framework systematically structures and monitors LLM-assisted qualitative coding while preserving human authority over coding decisions.