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[ARTICLE · art-66431] src=arxiv.org ↗ pub= topic=artificial-intelligence verified=true sentiment=↑ positive

Real-World Evaluation of an AI Agent Drafting Translational Impact Summaries

A human-in-the-loop AI agent built by a Clinical and Translational Science Award (CTSA) hub drafted Translational Science Benefits Model impact summaries for 10 career-development scholars, achieving an 81.7% unanimous usable rate across 507 findings and reducing staff time from an estimated 15 hours to a median of 14 minutes per scholar. Reviewers rated the agent's synthesis accuracy 4.5 and usefulness 4.8 on a 5-point scale, and the agent captured impact evidence across all four TSBM domains, including non-scholarly categories often missed by routine processes.

read1 min views2 publishedJul 21, 2026

arXiv:2607.16989v1 Announce Type: new Abstract: Introduction. Clinical and Translational Science Award (CTSA) programs must document their scholars' research impact, but assembling each scholar's record by hand takes staff an estimated 15 hours and does not scale to a full cohort. An artificial intelligence (AI) agent could serve as a tool to gather scholar data across platforms and disciplines. Methods. We built a human-in-the-loop AI agent that assembles a dossier of sourced evidence for each scholar and drafts one-sentence Translational Science Benefits Model (TSBM) impact summaries for staff review. We evaluated it in the impact-reporting workflow of one CTSA hub across 10 career-development (KL2/K12) scholars. Two evaluation staff independently coded all 507 findings as accept, edit, or reject; the primary measure was the unanimous usable rate, defined as the share both accepted or edited. Results. Both reviewers accepted or edited 81.7% of the agent's findings. Reviewers each spent a median of 14 minutes per scholar, replacing an estimated 15 hours of manual assembly. Inter-rater agreement was moderate (Cohen's kappa 0.43 on the usable-versus-reject decision). A profile discovery study found the agent's recall close to human search. The agent's impact evidence spanned all four TSBM domains, and about a third of the reviewed findings fell in non-scholarly categories that routine processes tend to miss. Reviewers rated synthesis accuracy 4.5 and usefulness 4.8 on a 5-point scale. Conclusions. A human-in-the-loop AI agent can serve as the first-pass author of a scholar's impact record, shifting staff from collecting and writing to reviewing, and making cohort-scale impact reporting feasible.

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