REAL-Q: E2E LLM Quantization via Dynamic Gradient Descent Researchers introduced REAL-Q (Real-time E2E-loss Aligned LLM Quantization), a post-training quantization method that uses dynamic Block-wise Gradient Descent to reduce end-to-end KL divergence by up to ~49% relative to state-of-the-art globally-guided methods on LLaMA-3.1 (8B and 70B) and Qwen3 (0.6B-32B) at W4A16. The method targets an end-to-end-aligned surrogate of the global loss and refines it after every column block of 128 columns, mitigating error propagation across the network. arXiv:2609.00049v1 Announce Type: new Abstract: Post-training quantization PTQ is essential for deploying large language models LLMs under strict resource constraints. State-of-the-art PTQ methods quantize each layer with a single closed-form second-order solver: to remain analytically tractable, they heavily approximate the global loss dropping cross-channel coupling, pooling output rows into groups , and they then freeze the resulting Hessian across the entire layer, with no way to refresh it as the loss landscape shifts column by column--a phenomenon we call information misalignment. We propose REAL-Q Real-time E2E-loss Aligned LLM Quantization , a novel PTQ paradigm that breaks this compromise: instead of diluting the objective for the sake of analytic tractability, REAL-Q targets an end-to-end-aligned surrogate of the global loss and refines it via fine-grained, dynamic Block-wise Gradient Descent applied after every column block 128 columns . By coupling this fine-grained correction with a sliding window mechanism for smooth cross-layer transitions, REAL-Q effectively mitigates error propagation across the network. On LLaMA-3.1 8B and 70B and Qwen3 0.6B-32B at W4A16, REAL-Q reduces end-to-end KL divergence by up to ~49% relative to state-of-the-art globally-guided methods.