OpenAI’s math breakthrough could hit biotech and pharma next An unreleased OpenAI model reportedly solved 90 of 500 of the hardest open math problems, spending about three hours on each, according to In The Loop host Ejaaz Ahamadeen. Ahamadeen said experts in every field, including biotech and pharma, are about to feel what mathematicians are feeling now. An unreleased OpenAI model reportedly solved 90 of 500 of the hardest open math problems, in about three hours each. In The Loop Host Ejaaz Ahamadeen breaks down why experts in every field are about to feel what mathematicians are feeling right now.