# New series of papers on Automatic experimental design with expert in the loop

> Source: <https://www.manchester.ac.uk/about/news/new-series-of-papers-on-automatic-experimental-design-with-expert-in-the-loop/>
> Published: 2026-07-29 13:30:48+00:00

These papers were the focus of two recent presentations, at the Bayesian Experimental Design workshop at [ Manchester Centre for AI Fundamentals](https://www.linkedin.com/company/ai-fun-mcr/) on 24 June, and at the

For unknowns in the model, the starting point is Bayesian inference: use data to update beliefs about what is uncertain, and, where possible, choose new measurements that are expected to be most useful. Bayesian decision theory provides the framework for selecting measurement actions, or other decisions, by maximising expected utility. Bayesian optimisation can be viewed as an important instance of this broader approach.

Although these ideas have been understood in principle for some time, the challenge has been computational: the calculations are often too expensive for interactive use in realistic experimental design settings. The papers in this series address that bottleneck through amortisation — an elegantly simple idea in spirit, where expensive online computation is shifted into offline pre-computation. In practice, this means learning from a large collection of simulated designs a function that maps an experimental design context or history to a strong next design choice.

Together, the papers extend this amortised approach in several directions: to multi-objective Bayesian optimisation, dimension-agnostic settings, preferential or pairwise inputs, and noisy or perturbed inputs from biased experts with partial knowledge. The result is a coherent line of work showing how expert-in-the-loop automatic experimental design can become more scalable, interactive and practically useful.