# Microsoft opens BioEmu2 weights to model biomolecular motion > Source: > Published: 2026-10-21 01:13:25+00:00 # Microsoft opens BioEmu2 weights to model biomolecular motion **Frank Noe's X thread says BioEmu2 can emulate molecular dynamics in minutes; Microsoft's model card frames it as research software, not a validated commercial tool.** By [Ryan Merket](https://runtimewire.com/author/ryan-merket) · Published Primary source: [X](https://x.com/FrankNoeBerlin/status/2112472173336240499) ## Why it matters BioEmu2 makes an open, research-stage model for biomolecular motion available to researchers. Its speed claims could help prioritize experiments and simulations, while Microsoft's own warnings make clear that the predictions still require validation. Microsoft Research has opened a public preview of [BioEmu2](https://runtimewire.com/models/huggingface/microsoft-bioemu2-f22f395a23a9e70d), an AI model designed to generate ensembles of biomolecular structures and simulate how those molecules move. In an [October 20th thread on X](https://x.com/FrankNoeBerlin/status/2112472173336240499?ref=runtimewire), [Frank Noe](https://www.microsoft.com/en-us/research/people/franknoe/?ref=runtimewire), a Partner Research Manager on Microsoft's AI for Science team, described the release as a step toward modeling biological processes at a scale that can complement work on gene… When you purchase through links in our articles, [we may earn a small commission](https://runtimewire.com/affiliate-monetization-standards). This doesn’t affect our editorial independence.