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MedJev: Evaluating Zero-Shot System-One Decision Making in Medicine

A new arXiv paper (2610.36006v1) evaluates MedJev, an open "System One" model that runs locally on a laptop and answers structured medical questions in a single forward pass, reporting accuracies of 72.5% on MedQA, 75.4% on USMLE and 80.1% on NEJM — approaching published GPT-4 results while keeping confidence estimates well calibrated (ECE 0.028 to 0.063). On patient-level tasks using MIMIC IV and MIMIC IV ED, MedJev reached an AUROC of 0.926 for in-hospital mortality, above XGBoost's 0.902, but trailed supervised models on ED triage admission (0.745 vs. 0.809) and showed substantial miscalibration on patient-level predictions (in-hospital mortality ECE 0.286). The authors introduce a two-parameter recalibration method using 50 to 200 labeled examples that cuts ECE to 0.007, and release their code and evaluation harness.

read1 min views6 publishedOct 28, 2026

arXiv:2610.36006v1 Announce Type: new Abstract: System One decision models such as Jev answer structured questions in a single forward pass without generating text, offering fast and computationally efficient clinical decision support. We evaluate MedJev, an open System One model that runs locally on a laptop, across ten medical benchmarks spanning medical knowledge, diagnosis, and patient level prediction using MIMIC IV and MIMIC IV ED. We compare MedJev against zero shot LLM baselines, published GPT results, and supervised models. MedJev achieves accuracies of 72.5 percent on MedQA, 75.4 percent on USMLE, and 80.1 percent on NEJM, approaching published GPT 4 performance while maintaining well calibrated confidence estimates (ECE 0.028 to 0.063). On patient level tasks, MedJev achieves an AUROC of 0.926 for In Hospital Mortality, exceeding XGBoost (0.902), but underperforms supervised models on operational outcomes such as ED Triage Admission (0.745 vs. 0.809). Patient level predictions also exhibit substantial miscalibration (In Hospital Mortality ECE 0.286). We introduce a lightweight, two parameter recalibration method that adapts predictions to local patient populations using 50 to 200 labeled examples, reducing ECE to 0.007. Our findings establish open System One models as a promising zero shot baseline for medical AI, combining competitive predictive performance with low computational cost and efficient local calibration. We release our code and evaluation harness to support future research.

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