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KANEx: Translating Kolmogorov-Arnold Networks' Interpretability to Medical Explainability

Researchers introduced KANEx, the first framework leveraging Kolmogorov-Arnold Networks (KANs) to ground Vision-Language Model (VLM) reasoning for medical explainability, achieving a 10% improvement in visual localization and downstream reasoning quality on the MIMIC-CXR dataset. The team also developed KAN-Map, a heatmap generation method derived directly from KAN models, demonstrating that KAN-based architectures with ResNet/ViT baselines produce more faithful saliency maps and improved semantic similarity. The findings indicate that grounding explanations in mathematically interpretable units is a necessary step toward trustworthy medical AI.

read1 min views1 publishedJul 28, 2026

arXiv:2607.24730v1 Announce Type: cross Abstract: Computer vision models have become highly effective for medical applications, yet their black-box nature continues to undermine clinician trust. In clinical workflows, chest X-ray classifiers are increasingly paired with Vision-Language Models (VLMs) to generate natural-language explanations. However, these systems add linguistic fluency without addressing the underlying opacity of the visual model. With the emergence of Kolmogorov-Arnold Networks (KANs), whose spline-based components provide inherently interpretable functional units, we investigate whether this architectural transparency can be leveraged to produce more trustworthy textual explanations. We introduce KANEx, the first ever framework that leverages the symbolic transparency of KANs to ground VLM reasoning. This interpretability also made it possible to design KAN-Map, a novel heatmap generation method derived directly from KAN models rather than gradient approximations. We feed these grounded contexts into downstream VLMs for enhanced explainability. Benchmarked on the MIMIC-CXR dataset, we demonstrate that KAN-based architectures with ResNet/ViT baselines demonstrate improved semantic similarity while producing significantly more faithful saliency maps. KAN architectures improve visual localization and downstream reasoning quality by 10%. Our findings suggest that grounding linguistic explanations and visual attributions in mathematically interpretable units is a necessary step toward trustworthy medical AI.

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