{"slug": "how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for", "title": "How Compliant is Sepsis Treatment? An Expert-Guided Neuro-symbolic Pipeline for Generating Clinical Compliance Insights", "summary": "A new expert-guided neuro-symbolic pipeline that combines a large language model with a Sugeno fuzzy inference system to assess compliance with sepsis treatment protocols found that antibiotic timing is the most critical breakdown, with a mean compliance score of 0.24 and only 13% of patients receiving antibiotics within one hour. Applied to 2,438 MIMIC-IV v3.1 sepsis episodes, the pipeline also revealed Hour-1 underperformance (mean 36.7%), a 51% drop-off in elevated-lactate measurement, and longer ICU stays for non-compliant patients (5.1 vs 3.8 days). The research, posted on arXiv (2608.13617v1), encodes eight Surviving Sepsis Campaign bundle rules into graded scores in [0,1].", "body_md": "arXiv:2608.13617v1 Announce Type: new\nAbstract: Verifying whether clinical care follows evidence-based protocols is a natural neuro-symbolic problem, yet the safety-critical setting defeats either paradigm alone. We present an expert-guided pipeline that constrains a large language model strictly to semantic normalization, mapping messy drug and microbiology strings onto a fixed clinical vocabulary, while a Sugeno fuzzy inference system reasons over the normalized events. The fuzzy layer encodes eight Surviving Sepsis Campaign bundle rules and replaces binary judgments with graded scores in [0,1]. Applied to 2,438 MIMIC-IV v3.1 sepsis episodes, it surfaces antibiotic timing as the most critical breakdown (mean 0.24, 13% within one hour), Hour-1 underperformance (mean 36.7%), a 51% elevated-lactate drop-off, and descriptive differences in ICU stay across compliance groups (3.8 versus 5.1 days).", "url": "https://wpnews.pro/news/how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for", "canonical_source": "https://arxiv.org/abs/2608.13617", "published_at": "2026-08-17 04:00:00+00:00", "updated_at": "2026-08-17 04:12:32.584307+00:00", "lang": "en", "topics": ["artificial-intelligence", "machine-learning", "large-language-models", "ai-research"], "entities": ["arXiv", "MIMIC-IV", "Surviving Sepsis Campaign"], "alternates": {"html": "https://wpnews.pro/news/how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for", "markdown": "https://wpnews.pro/news/how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for.md", "text": "https://wpnews.pro/news/how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for.txt", "jsonld": "https://wpnews.pro/news/how-compliant-is-sepsis-treatment-an-expert-guided-neuro-symbolic-pipeline-for.jsonld"}}