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EviGen: Predictive Evidence Scaffolding for Verifiable Clinical Rationale Generation

Researchers proposed EviGen, a three-layer framework for verifiable clinical rationale generation that uses a patient-conditioned retriever with learnable queries, an LLM generator, and a process-supervised verifier, according to an arXiv paper numbered 2609.18852v1. Across three medical prediction datasets, EviGen improved prediction performance and rationale faithfulness over full-context LLM and RAG baselines, and clinical reviewers preferred it in a usability evaluation.

by read1 min views1 publishedSep 17, 2026

arXiv:2609.18852v1 Announce Type: new Abstract: Longitudinal electronic health records (EHRs) capture years of patient history across notes, codes, labs, and procedures, and contain evidence needed to reason about likely clinical outcomes. However, comprehensive clinician review of these records is impractical, and LLM-based processing is costly and often unreliable, missing some relevant observations while hallucinating others. We therefore propose EviGen, a three-layer framework for verifiable clinical rationale generation that addresses these challenges. The first layer is a patient-conditioned retriever that uses learnable queries to find evidence predictive of, not just textually relevant to, a clinical outcome and ranks it by prediction attribution scores. The second layer is an LLM generator that consumes this ranked evidence as a scaffold to produce a clinical rationale grounded in the retrieved spans. The third layer is a process-supervised verifier that checks the generated rationale at the reasoning-step level, flagging unreliable claims. Across three medical prediction datasets, EviGen improves prediction performance and rationale faithfulness over full-context LLM and RAG baselines, and is preferred by clinical reviewers in a usability evaluation.

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