Epidemiology of Model Collapse: Modeling Synthetic Data Contamination via Bilayer SIR Dynamics Researchers have developed a bilayer SIR/SIRS epidemiological model to analyze how AI models collapse when trained on synthetic data generated by other AI systems, treating data corpora and AI models as two interacting populations. The model, which incorporates immunity waning and cross-layer transmission, finds that synthetic-data contamination is currently supercritical ($R_0 > 1$) across multiple scenarios, with detection-based filtering and herd immunity identified as the most effective interventions. Experiments using GPT-2 across WikiText and Shakespeare datasets confirmed dose-response degradation and diversity loss consistent with the threshold dynamics, while multi-source mixing showed only modest benefits at higher contamination levels. arXiv:2606.05168v1 Announce Type: new Abstract: Training on synthetic data causes model collapse, but existing analyses treat this as single-chain degradation. In reality, the AI ecosystem involves cross-contamination: models ingest synthetic data from other models, produce new synthetic text, and contaminate shared corpora. We propose a bilayer coupled SIR/SIRS framework -- a phenomenological mean-field model treating data corpora and AI models as two interacting populations, each with susceptible, infected, and recovered compartments linked by cross-layer transmission. The SIRS variant our primary recommendation incorporates immunity waning, reflecting that filtered corpora and retrained models remain susceptible to re-contamination. We derive the basic reproduction number $R 0 = \sqrt{\beta D \beta M / \gamma D+\mu D \gamma M+\mu M }$ via the Next Generation Matrix and apply standard epidemic threshold results to the bilayer system. Illustrative scenario-based calibration from public AI text prevalence data yields supercritical dynamics $R 0 1$ across three scenarios; Sobol sensitivity analysis identifies synthetic-text detection as the highest-leverage parameter. A bipartite-network agent-based model confirms mean-field consistency $R^2 0.96$ for dense networks but degrades under heterogeneity. GPT-2 contamination chain experiments 192 runs across WikiText and Shakespeare show dose-response degradation and diversity loss qualitatively consistent with the threshold picture. Matched-budget source-diversity experiments 1,088 runs provide suggestive evidence that multi-source mixing modestly attenuates collapse, but the effect vanishes at lower contamination fractions. Intervention analysis identifies detection-based filtering and herd immunity as the highest-leverage strategies.