cd /news/machine-learning/end-to-end-differentiable-diffusion-… · home › topics › machine-learning › article
[ARTICLE · art-158454] src=arxiv.org ↗ pub= topic=machine-learning verified=true sentiment=↑ positive

End-to-End Differentiable Diffusion Conditioning for Physics-Informed Optimization

A new arXiv paper (2610.31721v1) introduces Differentiable Diffusion Conditioning (D2C), an offline model-based optimization method that turns a frozen conditional diffusion model into an end-to-end gradient-based optimizer by backpropagating gradients from frozen surrogate objectives and physics-informed penalties through the reverse denoising chain. The authors report D2C achieved the strongest results on two real-world tasks — laser pulse optimization for inertial confinement fusion and sustainable data-center workload scheduling — and the best average rank across four Design-Bench tasks. The method is implemented in a composed proposer-evaluator framework and targets the conservatism and unconstrained surrogate exploitation that limit existing offline MBO approaches.

by read1 min views1 publishedOct 27, 2026

arXiv:2610.31721v1 Announce Type: new Abstract: Optimizing high-dimensional physical systems under expensive evaluations and complex constraints is a central challenge in science and engineering. In offline model-based optimization (MBO), methods must improve designs using only a fixed dataset and no test-time access to the true objective. However, existing methods typically suffer from conservatism, unconstrained surrogate exploitation, or function as static inference-time samplers that cannot refine candidates against precise physical objectives. In this paper, we propose Differentiable Diffusion Conditioning (D2C) for offline MBO, which leverages the fact that deterministic sampling makes the reverse denoising chain differentiable with respect to the conditioning signal. D2C turns a frozen conditional diffusion model into an end-to-end gradient-based optimizer by directly optimizing conditioning variables at test time via gradients from frozen surrogate objectives and physics-informed penalties backpropagated through the reverse chain. We implement this idea in a composed proposer-evaluator framework and evaluate it on laser pulse optimization for inertial confinement fusion, sustainable data-center workload scheduling, and four Design-Bench tasks. Our method achieves the strongest results on the two real-world tasks and the best average rank across four Design-Bench tasks.

── more in #machine-learning 4 stories · sorted by recency
── more on @arxiv 3 stories trending now
sponsored brought to you by zahid.host 4,200+ EU-deployed projects
reading about agents? ship yours in a single git push.

Run your AI side-project on zahid.host

EU-based hosting, git-push deploys, automatic HTTPS, no cold starts. Free tier with a custom domain — perfect for shipping the agent you just read about.

$git push zahid main
→ Live at https://your-agent.zahid.host ✓
Get free account → Pricing
from €0/mo · no card required
LIVE [news/end-to-end-different…] indexed:0 read:1min 2026-10-27 · —