AMD Advances the Instinct MI400 Series for AI AMD reported that its Instinct MI455X GPU, running in the AMD Helios rackscale solution, delivered 21,333 tokens per second per GPU on DeepSeek-R1 in an MLPerf Inference Offline configuration, up to 30% higher throughput than Nvidia Vera Rubin's latest published MLPerf offline result. AMD also introduced the Instinct MI450X GPU, which offers 288 GB of HBM4 memory per GPU with the same core compute, memory bandwidth and scale-up/scale-out connectivity as the MI455X, giving Helios customers a second memory-capacity option. AMD said Helios provides up to 20% higher HBM bandwidth and higher scale-up bandwidth than Nvidia Vera Rubin. What’s the News? AMD is advancing the AMD Instinct™ MI400 Series GPU portfolio with updates on performance and a new product option for customers. AMD is sharing new measured inference results for the AMD Instinct™ MI455X GPU on the AMD Helios™ rackscale solution and is introducing the AMD Instinct™ MI450X GPU, giving AMD Helios customers another option to match memory capacity with their AI workloads and deployment needs. Why It Matters? Frontier AI and interactive inference demand different balances of performance, memory capacity and responsiveness. MI400 Series GPUs address those needs by giving customers choice of memory capacities with the same leadership compute capabilities of AMD Helios. What’s the Role of AMD? How Is MI455X Advancing AI Performance? New AMD testing demonstrates leadership inference performance on MI455X powering AMD Helios delivering 21,333 tokens per second per GPU on DeepSeek-R1 using an MLPerf Inference Offline configuration – resulting in up to 30% higher throughput than the Nvidia Vera Rubin latest published MLPerf offline result. 1 fn-1 AMD Helios further extends its infrastructure leadership with up to 20% higher HBM bandwidth