{"slug": "alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic", "title": "AlphaGenome Atlas: Google DeepMind's New AI Tool Decodes Every Possible Genetic Mutation", "summary": "Google DeepMind has launched AlphaGenome Atlas, a free platform offering predictions for 9 billion possible single-nucleotide variants, covering every single-letter DNA change in the human genome. The dataset is over 30 times larger than the AlphaFold Database and includes both coding and non-coding regions. Researchers at the Broad Institute used the platform's AlphaGenome Variant Impact (AVI) score to uncover a previously overlooked variant in the DNM1 gene linked to epileptic encephalopathy, and a University of Exeter fellow found 22% more non-coding genetic associations in UK Biobank data.", "body_md": "DeepMind's AlphaGenome Atlas Uncovers Rare Disease Clues Hidden in Human DNA\n\nBy Mashable News Staff\n\nGoogle DeepMind has launched AlphaGenome Atlas, a free platform offering predictions for 9 billion possible single-nucleotide variants, which is essentially every single-letter DNA change possible in the human genome!\n\nAt 1 petabyte, the dataset is over 30 times larger than the AlphaFold Database, and it covers both coding regions (2% of the genome) and non-coding regions (98%) that regulate gene activity.\n\nThe platform introduces the AlphaGenome Variant Impact (AVI) score, which merges predictions from AlphaGenome and AlphaMissense into one number, letting researchers rank and interpret variants simultaneously.\n\nResearchers at the Broad Institute used the AVI score to uncover a previously overlooked variant in the DNM1 gene, linking it to epileptic encephalopathy through an abnormal splice site mutation.\n\nA University of Exeter fellow applied the Atlas to genome data from over 54,000 UK Biobank participants and found 22% more non-coding genetic associations tied to protein levels, including genes linked to aging and oxygen sensing.\n\nThe same UK Biobank analysis identified 19 genetic regions potentially linked to body mass index by isolating the top 1% of predicted high-impact non-coding variants.\n\nAlphaGenome Atlas is available now for non-commercial academic use via a website portal and API, with commercial access on Google Cloud planned soon, and it can also integrate into Google's Antigravity agentic research system. If this is your area of research, then follow the rabbit trail.", "url": "https://wpnews.pro/news/alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic", "canonical_source": "https://in.mashable.com/science/113749/alphagenome-atlas-google-deepminds-new-ai-tool-decodes-every-possible-genetic-mutation", "published_at": "2026-09-08 16:34:28+00:00", "updated_at": "2026-09-08 16:56:07.297260+00:00", "lang": "en", "topics": ["artificial-intelligence", "ai-products", "ai-research", "ai-tools"], "entities": ["Google DeepMind", "AlphaGenome Atlas", "AlphaFold Database", "Broad Institute", "University of Exeter", "UK Biobank", "DNM1"], "alternates": {"html": "https://wpnews.pro/news/alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic", "markdown": "https://wpnews.pro/news/alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic.md", "text": "https://wpnews.pro/news/alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic.txt", "jsonld": "https://wpnews.pro/news/alphagenome-atlas-google-deepmind-s-new-ai-tool-decodes-every-possible-genetic.jsonld"}}