{"slug": "ai-solves-18-medical-mysteries-in-total-game-changer-for-patients", "title": "AI solves 18 medical mysteries in ‘total game changer’ for patients", "summary": "A new study in NEJM AI found that OpenAI's o3 model helped diagnose 18 children with previously unsolved medical mysteries at Boston Children's Hospital, including rare neurodevelopmental and neuromuscular disorders. The AI analyzed 376 genomes and identified nearly 5% new diagnoses, a breakthrough described as a 'total game changer' for patients like Kyra Benton, who finally received a diagnosis after years of symptoms.", "body_md": "# AI solves 18 medical mysteries in ‘total game changer’ for patients\n\n- A new study published in\n*NEJM AI*indicates that OpenAI’s o3 model can help diagnose previously unsolved medical mysteries. - The AI model, released in April 2025, assisted in identifying new diagnoses for 18 children at Boston Children’s Hospital, including those with rare neurodevelopmental and neuromuscular disorders.\n- Researchers analysed 376 genomes from undiagnosed patients, with the AI model successfully identifying nearly five per cent of new diagnoses, a result described as a “total game changer.”\n- One patient, Kyra Benton, who had experienced undiagnosed symptoms since age nine, finally received a diagnosis of myofibrillar myopathy with the aid of the AI.\n- The study highlights that the AI model functions as a diagnostic tool, processing patient data and doctors' notes, with human review essential for final diagnoses, and is not intended for self-diagnosis.", "url": "https://wpnews.pro/news/ai-solves-18-medical-mysteries-in-total-game-changer-for-patients", "canonical_source": "https://www.independent.co.uk/bulletin/news/ai-children-boston-medical-mysteries-b2999643.html", "published_at": "2026-06-20 14:28:58+00:00", "updated_at": "2026-06-20 14:44:38.544299+00:00", "lang": "en", "topics": ["artificial-intelligence", "machine-learning", "ai-research", "ai-products", "ai-ethics"], "entities": ["OpenAI", "Boston Children's Hospital", "NEJM AI", "Kyra Benton", "o3 model"], "alternates": {"html": "https://wpnews.pro/news/ai-solves-18-medical-mysteries-in-total-game-changer-for-patients", "markdown": "https://wpnews.pro/news/ai-solves-18-medical-mysteries-in-total-game-changer-for-patients.md", "text": "https://wpnews.pro/news/ai-solves-18-medical-mysteries-in-total-game-changer-for-patients.txt", "jsonld": "https://wpnews.pro/news/ai-solves-18-medical-mysteries-in-total-game-changer-for-patients.jsonld"}}