{"slug": "a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial", "title": "A kill switch for epilepsy? China cuts seizures by 92.6% in first human chemogenetic trial", "summary": "A first-in-human chemogenetic trial in China reduced seizures by 92.6% in a patient with refractory epilepsy, according to the trial's reported results. The approach uses a chemogenetic system to suppress abnormal neural discharges in the brain, targeting the roughly one-third of epilepsy patients worldwide who do not respond to existing medications and for whom craniotomy resection carries a risk of irreversible neurological damage.", "body_md": "For people living with refractory epilepsy, the brain is like a city that can suffer a blackout any time lightning strikes.\nWithout warning, an abnormal neural discharge can sweep through the intracranial circuits, leaving behind convulsions, loss of consciousness and years of lingering panic.\nAround one-third of epilepsy patients worldwide are completely unresponsive to existing medications, while traditional craniotomy resection surgery often carries the risk of irreversible neurological...", "url": "https://wpnews.pro/news/a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial", "canonical_source": "https://www.scmp.com/news/china/science/article/3373500/kill-switch-epilepsy-china-cuts-seizures-926-first-human-chemogenetic-trial", "published_at": "2026-11-06 13:00:08+00:00", "updated_at": "2026-11-06 13:23:28.027904+00:00", "lang": "en", "topics": ["artificial-intelligence", "ai-research"], "entities": ["China"], "also_reported_by": [], "alternates": {"html": "https://wpnews.pro/news/a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial", "markdown": "https://wpnews.pro/news/a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial.md", "text": "https://wpnews.pro/news/a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial.txt", "jsonld": "https://wpnews.pro/news/a-kill-switch-for-epilepsy-china-cuts-seizures-by-92-6-in-first-human-trial.jsonld"}}